inotropic effect वाक्य
उदाहरण वाक्य
मोबाइल
- Endothelin receptor activation mediates strong pulmonary vasoconstriction and positive inotropic effect on the heart.
- Disopyramide has a negative inotropic effect on the ventricular myocardium, significantly decreasing the contractility.
- Antianginal effects result from negative chronotropic and inotropic effects, which decrease cardiac workload and oxygen demand.
- Hypercalcemia can result in an increase in heart rate and a positive inotropic effect ( increase in contractility ).
- Calcium channel blockers are generally contraindicated due to their negative inotropic effect, particularly in cardiomyopathy caused by amyloidosis.
- The calcium channel blockers typically used are verapamil and diltiazem, because of their combined vasodilator and negative inotropic effects.
- The parasympathetic nervous system, through the action of vagus nerve, exerts a negative inotropic effect upon the heart.
- Because of the negative inotropic effects, the nondihydropyridine calcium channel blockers should be avoided ( or used with caution ) in individuals with cardiomyopathy.
- The primary antihypertensive mechanism of beta blockers is unclear, but may involve reduction in cardiac output ( due to negative chronotropic and inotropic effects ).
- Onmel / Sporanox ( Itraconazole ) exhibits a negative inotropic effect on the heart and thus could spur an additive effect when used concomitantly with Isradipine.
- T 1 AM may be part of a signaling pathway to modulate cardiac function, as the compound can induce negative inotropic effects and decrease cardiac output.
- The latter property ( positive chronotropic and inotropic effects ) is particularly important, because other vasodilators used in angina may be counter productive causing coronary steal phenomenon.
- In higher concentrations it causes endothelium-independent vasodilation and has a negative inotropic effect on cardiac output function, thus effectively lowering blood pressure and myocardial oxygen consumption.
- Non-dihydropyridine calcium channel blockers such as verapamil block the slow inward calcium current in cardiac tissues, thereby having a negatively dromotropic, chronotropic and inotropic effect.
- In addition, since SERCA is more active, the next action potential will cause an increased release of calcium, resulting in increased contraction ( positive inotropic effect ).
- The mechanism of action is through inhibiting the breakdown and thereby increasing the concentration of cAMP similar to beta adrenoreceptor agonism, resulting in inotropic effects and modest diuretic effects.
- Cassaine can be defined as a specific inhibitor of monovalent cation transport and of Na +-K + ATPase; the result being an inotropic effect on cardiac muscle.
- Because of the negative inotropic effects of flecainide, it should be used with caution in individuals with depressed ejection fraction, and may worsen congestive heart failure in these individuals.
- Noradrenaline ( a . k . a . norepinephrine ) is an inotrope and has a positive inotropic effect on heart muscle, when binding to beta-1 adrenergic receptors on this tissue.
- Disopyramide s particular efficacy is due to its potent negative inotropic effects; in head-to-head comparison, it is more effective for gradient reduction than either beta-blocker or verapamil.
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